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FIBP O43427

酸性成纤维细胞生长因子胞内结合蛋白 (aFGF胞内结合蛋白) (FGF-1胞内结合蛋白)

蛋白质信息 (UniProt)

酸性成纤维细胞生长因子胞内结合蛋白 (aFGF胞内结合蛋白) (FGF-1胞内结合蛋白)

O43427

功能描述

可能参与FGF1的促有丝分裂功能。可能与IER2一起介导胚胎侧性建立中的FGF信号传导 (By similarity)。 {ECO:0000250|UniProtKB:Q6T938, ECO:0000269|PubMed:9806903}。

组织特异性

Highly expressed in heart, skeletal muscle and pancreas. Expressed at lower levels in brain. Also found in placenta, liver and kidney.

亚细胞定位

Nucleus. Endomembrane system; Peripheral membrane protein. Note=Also associated with cytoplasmic membranes, particularly of mitochondria.

关键词

Acetylation Alternative splicing Disease variant Membrane Nucleus Proteomics identification Reference proteome