FHOD3 Q2V2M9

含FH1/FH2结构域蛋白3 (Formactin-2) (脾脏过表达Formin同源物2) (hFHOS2)

功能描述

功能：肌动蛋白组织蛋白，可能引起应力纤维形成并伴随细胞伸长（根据相似性）。异构体4可能在心肌细胞的肌动蛋白丝聚合中发挥作用。{ECO:0000250, ECO:0000269|PubMed:21149568}。

组织特异性

Expressed in the heart, kidney and brain. May be down-regulated in various types of heart diseases, including idiopathic dilated, ventricular dilated, familial dilated and perinatal dilated cardiomyopathies, as well as ischemic heart disease (at protein level).

亚细胞定位

Cytoplasm, cytoskeleton