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FCRL2 Q96LA5

Fc受体样蛋白2 (FcR样蛋白2) (FcRL2) (Fc受体同源物2) (FcRH2) (IFGP家族蛋白4) (免疫球蛋白受体易位相关蛋白4) (含SH2结构域磷酸酶锚定蛋白1) (CD抗原CD307b)

蛋白质信息 (UniProt)

Fc受体样蛋白2 (FcR样蛋白2) (FcRL2) (Fc受体同源物2) (FcRH2) (IFGP家族蛋白4) (免疫球蛋白受体易位相关蛋白4) (含SH2结构域磷酸酶锚定蛋白1) (CD抗原CD307b)

Q96LA5

功能描述

可能在正常和肿瘤性B细胞发育中具有调节作用。 {ECO:0000269|PubMed:11493702}.

组织特异性

Expressed in the secondary lymphoid organs, spleen and lymph node. Expression is limited to the mature B-cell lines. Highly expressed in CD19 and within the mantle zones of the tonsil tissue. Isoform 2 is expressed in the spleen, peripheral blood and bone marrow. Isoform 2 and isoform 4 are expressed in B-cell lines. Preferentially expressed in memory B-cells (at protein level).

亚细胞定位

Cell membrane

关键词

Alternative splicing Cell membrane Direct protein sequencing Disulfide bond Glycoprotein Immunoglobulin domain Membrane Proteomics identification Receptor Reference proteome