Fas结合因子1 (FBF-1) (Albatross蛋白)
Fas结合因子1 (FBF-1) (Albatross蛋白)
Q8TES7功能描述
上皮细胞极化所需的角蛋白结合蛋白。通过与PARD3相互作用参与顶端连接复合体(AJC)的组装。纤毛发生所必需的。 {ECO:0000269|PubMed:18838552, ECO:0000269|PubMed:23348840}。
组织特异性
Present in various epithelial cells (at protein level).
亚细胞定位
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, spindle pole. Cell junction. Note=Localizes specifically to the distal appendage region of the centriole, which anchors the mother centriole to the plasma membrane. Localizes to the apical junction complex (AJC) in epithelial cells.
关键词