原钙黏蛋白Fat 2 (hFat2) (钙黏蛋白家族成员8) (多表皮生长因子样结构域蛋白1) (多EGF样结构域蛋白1)
原钙黏蛋白Fat 2 (hFat2) (钙黏蛋白家族成员8) (多表皮生长因子样结构域蛋白1) (多EGF样结构域蛋白1)
Q9NYQ8功能描述
参与细胞迁移的调控 (PubMed:18534823)。可能参与介导小脑发育过程中颗粒细胞平行纤维的组织 (By similarity)。 {ECO:0000250|UniProtKB:O88277, ECO:0000269|PubMed:18534823}。
组织特异性
Expressed in epidermal keratinocytes, infant brain, cerebellum, and also in a variety of tumors, such as pancreatic cancer, diffuse type gastric cancer, ovarian cancer, esophageal cancer, skin squamous cell carcinoma, head and neck cancer. Not expressed in melanoma cell line A375 cells, normal epidermal melanocytes or normal dermal fibroblasts. Expressed in epidermal keratinocytes and squamous cell carcinoma (at protein level).
亚细胞定位
Cell membrane
关键词