FAS相关因子1 (hFAF1) (含UBX结构域蛋白12) (含UBX结构域蛋白3A)
FAS相关因子1 (hFAF1) (含UBX结构域蛋白12) (含UBX结构域蛋白3A)
Q9UNN5功能描述
泛素结合蛋白 (PubMed:19722279)。通过靶向DNA复制许可因子CDT1进行降解，从而促进DNA复制叉的进程 (PubMed:26842564)。增强但不能启动FAS诱导的细胞凋亡 (By similarity)。 {ECO:0000250|UniProtKB:P54731, ECO:0000269|PubMed:19722279, ECO:0000269|PubMed:26842564}.
组织特异性
Most abundant in testis, slightly less abundant in skeletal muscle and heart, followed by prostate, thymus, ovary, small intestine, and colon. Not detected in the peripheral blood leukocytes.
亚细胞定位
Nucleus
关键词