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F2RL3 Q96RI0

蛋白酶激活受体4 (PAR-4) (凝血因子II受体样3) (凝血酶受体样3)

蛋白质信息 (UniProt)

蛋白酶激活受体4 (PAR-4) (凝血因子II受体样3) (凝血酶受体样3)

Q96RI0

功能描述

活化凝血酶或胰蛋白酶的受体,与刺激磷酸肌醇水解的G蛋白偶联 (PubMed:10079109)。可能在血小板活化中发挥作用 (PubMed:10079109)。 {ECO:0000269|PubMed:10079109}。

组织特异性

Widely expressed, with highest levels in lung, pancreas, thyroid, testis and small intestine. Not expressed in brain, kidney, spinal cord and peripheral blood leukocytes. Also detected in platelets.

亚细胞定位

Cell membrane; Multi-pass membrane protein.

关键词

3D-structure Blood coagulation Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Hemostasis Membrane Proteomics identification Receptor