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F2RL2 O00254

蛋白酶激活受体3 (PAR-3) (凝血因子II受体样2) (凝血酶受体样2)

蛋白质信息 (UniProt)

蛋白酶激活受体3 (PAR-3) (凝血因子II受体样2) (凝血酶受体样2)

O00254

功能描述

活化凝血酶的受体,与G蛋白偶联以刺激磷酸肌醇水解。 {ECO:0000269|PubMed:10079109}。

组织特异性

Highest expression in the megakaryocytes of the bone marrow, lower in mature megakaryocytes, in platelets and in a variety of other tissues such as heart and gut.

亚细胞定位

Cell membrane; Multi-pass membrane protein.

关键词

Alternative splicing Blood coagulation Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Hemostasis Membrane Proteomics identification Receptor