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EYS Q5T1H1

眼睛闭合蛋白同源物 (表皮生长因子样蛋白10) (EGF样蛋白10) (表皮生长因子样蛋白11) (EGF样蛋白11) (间隔蛋白同源物)

蛋白质信息 (UniProt)

眼睛闭合蛋白同源物 (表皮生长因子样蛋白10) (EGF样蛋白10) (表皮生长因子样蛋白11) (EGF样蛋白11) (间隔蛋白同源物)

Q5T1H1

功能描述

维持光感受器细胞的完整性所必需 (PubMed:18836446)。特别是光感受器纤毛袋正常形态所必需,因此可能通过过渡区促进光感受器内外节之间的蛋白质运输 (By similarity)。 {ECO:0000250|UniProtKB:B8JI71, ECO:0000269|PubMed:18836446}。

组织特异性

Expressed in retina (at protein level) (PubMed:18836446, PubMed:18976725, PubMed:27737822, PubMed:27846257). Isoform 1: Detected in retina (PubMed:27846257). Isoform 2: Detected in retina (PubMed:27846257). Isoform 3: Strongly expressed in retina and testis (PubMed:27846257). Isoform 4: Strongly expressed in testis, and weakly expressed in retina (PubMed:27846257).

亚细胞定位

Cell projection, cilium, photoreceptor outer segment

关键词

Alternative splicing Calcium Cell projection Cytoplasm Cytoskeleton Disease variant Disulfide bond EGF-like domain Extracellular matrix Glycoprotein