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EVI5 O60447

嗜同性病毒整合位点5蛋白同源物 (EVI-5) (神经母细胞瘤4S期基因蛋白)

蛋白质信息 (UniProt)

嗜同性病毒整合位点5蛋白同源物 (EVI-5) (神经母细胞瘤4S期基因蛋白)

O60447

功能描述

通过在间期稳定FBXO5蛋白并促进cyclin-A积累,作为细胞周期进程的调节因子发挥作用。可能在胞质分裂中发挥作用。 {ECO:0000269|PubMed:16439210}。

组织特异性

Expressed in various cell lines (at protein level). Expressed in a wide range of tissues including brain and adrenal.

亚细胞定位

Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Note=Associates with the mitotic spindle through anaphase and remains within the midzone and midbody until completion of cytokinesis.

关键词

Alternative splicing Cell cycle Cell division Chromosomal rearrangement Coiled coil Cytoplasm Cytoskeleton Nucleus Phosphoprotein Proteomics identification