嗜同性病毒整合位点5蛋白同源物 (EVI-5) (神经母细胞瘤4S期基因蛋白)
嗜同性病毒整合位点5蛋白同源物 (EVI-5) (神经母细胞瘤4S期基因蛋白)
O60447功能描述
通过在间期稳定FBXO5蛋白并促进cyclin-A积累,作为细胞周期进程的调节因子发挥作用。可能在胞质分裂中发挥作用。 {ECO:0000269|PubMed:16439210}。
组织特异性
Expressed in various cell lines (at protein level). Expressed in a wide range of tissues including brain and adrenal.
亚细胞定位
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Note=Associates with the mitotic spindle through anaphase and remains within the midzone and midbody until completion of cytokinesis.
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