EURL Q9NYK6

EURL蛋白同源物

功能描述

在皮层祖细胞增殖和分化中起作用。通过调节beta-catenin信号通路，促进迁移后皮层投射神经元的树突棘发育。 {ECO:0000250|UniProtKB:Q9D7G4}。

组织特异性

Expressed in the brain (PubMed:27404227). Expressed in cortical cells of the germinal ventricular zone and the cortical plate. Underexpressed in the dorsolateral prefrontal cortex, primary visual cortex and cerebellar cortex compared with Down Syndrome patients (at protein level) (PubMed:27404227).