ETS易位变异体1 (Ets相关蛋白81)
ETS易位变异体1 (Ets相关蛋白81)
P50549功能描述
转录激活因子，结合含有共有五核苷酸序列 5'-CGGA[AT]-3' 的 DNA 序列 (PubMed:7651741)。嗅觉多巴胺能神经元分化所必需；可能直接激活酪氨酸羟化酶 (TH) 的表达 (By similarity)。 {ECO:0000250|UniProtKB:P41164, ECO:0000269|PubMed:7651741}。
组织特异性
Very highly expressed in brain, highly expressed in testis, lung and heart, moderately in spleen, small intestine, pancreas and colon, weakly in liver, prostate and thymus, very weakly in skeletal muscle, kidney and ovary and not in placenta and peripheral blood leukocytes.
亚细胞定位
Nucleus
关键词