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ENPEP Q07075

谷氨酰氨基肽酶 (EAP) (EC 3.4.11.7) (氨基肽酶A) (AP-A) (分化抗原gp160) (CD抗原CD249)

蛋白质信息 (UniProt)

谷氨酰氨基肽酶 (EAP) (EC 3.4.11.7) (氨基肽酶A) (AP-A) (分化抗原gp160) (CD抗原CD249)

Q07075

功能描述

通过其钙调节的偏好性切割肽(如血管紧张素II)的N端酸性残基来调节中枢性高血压。 {ECO:0000305|PubMed:23888046}。

组织特异性

Expressed in choriocarcinoma cancer cell lines (at protein level) (PubMed:10692253). Expressed by epithelial cells of the proximal tubule cells and the glomerulus of the nephron. Also found in a variety of other tissues.

亚细胞定位

Cell membrane

关键词

3D-structure Aminopeptidase Calcium Cell membrane Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Membrane Metal-binding