胞外NOX二硫键-硫醇交换蛋白1 (候选生长相关及计时组成性氢醌[NADH]氧化酶) (cCNOX) (细胞增殖诱导基因38蛋白) (组成性胞外NOX) (cNOX) [包含：氢醌[NADH]氧化酶 (EC 1.-.-.-); 蛋白质二硫键-硫醇氧化还原酶 (EC 1.-.-.-)]
胞外NOX二硫键-硫醇交换蛋白1 (候选生长相关及计时组成性氢醌[NADH]氧化酶) (cCNOX) (细胞增殖诱导基因38蛋白) (组成性胞外NOX) (cNOX) [包含：氢醌[NADH]氧化酶 (EC 1.-.-.-); 蛋白质二硫键-硫醇氧化还原酶 (EC 1.-.-.-)]
Q8TC92功能描述
可能作为质膜电子传递的末端氧化酶，将细胞质NAD(P)H经由氢醌传递至细胞表面的受体。氢醌氧化酶活性与蛋白质二硫键-硫醇互换/氧化还原酶活性交替进行，这可能控制与囊泡出芽或细胞增大相关的物理膜位移。这些活性以24分钟的周期振荡，并在调控超日细胞生物钟中发挥作用。 {ECO:0000269|PubMed:11360993, ECO:0000269|PubMed:12565167, ECO:0000269|PubMed:17027975, ECO:0000269|PubMed:19055324}.
组织特异性
Expressed in lymphocyte cells, breast and breast cancer (at protein level). Found in the sera of cancer patients with a wide variety of cancers including breast, prostate, lung and ovarian cancers, leukemias, and lymphomas. Found also in the serum of healthy volunteers or patients with disorders other than cancer. Probably shed into serum by cancer cells.
亚细胞定位
Cell membrane
关键词