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ENO2 P09104

γ-烯醇化酶 (EC 4.2.1.11) (2-磷酸-D-甘油酸水裂解酶) (烯醇化酶2) (神经烯醇化酶) (神经元特异性烯醇化酶) (NSE)

蛋白质信息 (UniProt)

γ-烯醇化酶 (EC 4.2.1.11) (2-磷酸-D-甘油酸水裂解酶) (烯醇化酶2) (神经烯醇化酶) (神经元特异性烯醇化酶) (NSE)

P09104

功能描述

烯醇化酶,在糖酵解过程中催化2-磷酸甘油酸转化为磷酸烯醇丙酮酸,并在糖异生过程中催化逆反应 (By similarity)。对广泛的中枢神经系统 (CNS) 神经元具有神经营养和神经保护特性。以钙依赖性方式结合培养的新皮层神经元并促进细胞存活 (By similarity)。 {ECO:0000250|UniProtKB:P06733, ECO:0000250|UniProtKB:P07323}。

组织特异性

The alpha/alpha homodimer is expressed in embryo and in most adult tissues. The alpha/beta heterodimer and the beta/beta homodimer are found in striated muscle, and the alpha/gamma heterodimer and the gamma/gamma homodimer in neurons.

亚细胞定位

Cytoplasm

关键词

3D-structure Acetylation Alternative splicing Cell membrane Cytoplasm Direct protein sequencing Glycolysis Hydroxylation Isopeptide bond Lyase