ELF2 Q15723

ETS相关转录因子 Elf-2 (E74样因子 2) (新ETS相关因子)

功能描述

Isoform 1 转录激活 LYN 和 BLK 启动子，并与 RUNX1 协同反式激活 BLK 启动子。; FUNCTION: Isoform 2 可能在抑制 RUNX1 介导的反式激活中发挥作用。

组织特异性

Expressed in all fetal and adult tissues examined. Among fetal tissues, highest levels of expression detected in heart, lung, liver and kidney, and lower levels in brain. Among adult tissues, highest levels of expression detected in heart, placenta, lung, skeletal muscle, spleen, thymus, testis and ovary. Moderate expression in prostate, small intestine, kidney, liver and pancreas, and weak expression in colon, brain and peripheral blood lymphocytes.

亚细胞定位

Nucleus.