ETS相关转录因子Elf-1 (E74样因子1)
ETS相关转录因子Elf-1 (E74样因子1)
P32519功能描述
激活LYN和BLK启动子的转录因子。似乎为T细胞受体介导的HIV-2基因表达反式激活所必需。特异性结合HIV-2增强子中的两个富含嘌呤基序。 {ECO:0000269|PubMed:8756667}。
组织特异性
In fetal tissues, it is highly expressed in heart, lung liver and kidney, and weakly expressed in brain. In adult, it is highly expressed in pancreas, spleen, thymus and peripheral blood leukocytes, expressed at moderate levels in heart, placenta, lung, liver, skeletal muscle, kidney, prostate, ovary, small intestine and colon, and weakly expressed in brain and testis.
亚细胞定位
Nucleus.
关键词