EIF4G2 P78344

真核翻译起始因子4γ2 (eIF-4-gamma 2) (eIF-4G 2) (eIF4G 2) (死亡相关蛋白5) (DAP-5) (p97)

蛋白质信息 (UniProt)

真核翻译起始因子4γ2 (eIF-4-gamma 2) (eIF-4G 2) (eIF4G 2) (死亡相关蛋白5) (DAP-5) (p97)

P78344

功能描述

似乎在有丝分裂、细胞凋亡和病毒感染期间，从依赖cap的翻译向IRES介导的翻译转换过程中发挥作用。被某些caspase和病毒蛋白酶切割。 {ECO:0000269|PubMed:11511540, ECO:0000269|PubMed:11943866, ECO:0000269|PubMed:9032289, ECO:0000269|PubMed:9049310}。

组织特异性

Ubiquitously expressed in all adult tissues examined, with high levels in skeletal muscle and heart. Also expressed in fetal brain, lung, liver and kidney.

关键词

3D-structure Acetylation Alternative splicing Direct protein sequencing Initiation factor Isopeptide bond Methylation Phosphoprotein Protein biosynthesis Proteomics identification

外部链接

UniProt: P78344

NCBI Gene

GeneCards