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ECRG4 Q9H1Z8

Augurin(食管癌相关基因4蛋白)(ECRG4)

蛋白质信息 (UniProt)

Augurin(食管癌相关基因4蛋白)(ECRG4)

Q9H1Z8

功能描述

可能的激素,可能减弱细胞增殖并诱导中枢神经系统中少突胶质细胞和神经前体细胞的衰老 (By similarity)。ECRG4诱导的衰老特征为G1期阻滞、RB1去磷酸化以及CCND1和CCND3蛋白酶体降解加速 (By similarity)。 {ECO:0000250|UniProtKB:D4A540}。

组织特异性

Expressed in the brain, with expression in the epithelial cell layer of the choroid plexus (at protein level).

亚细胞定位

Secreted

关键词

Cell membrane Cleavage on pair of basic residues Cytoplasm Membrane Proteomics identification Reference proteome Secreted Signal