ECE1 P42892

内皮素转化酶1 (ECE-1) (EC 3.4.24.71)

功能描述

将大内皮素-1转化为内皮素-1。 {ECO:0000269|PubMed:37835445, ECO:0000269|PubMed:9396733}.

组织特异性

All isoforms are expressed in umbilical vein endothelial cells, polynuclear neutrophils, fibroblasts, atrium cardiomyocytes and ventricles. Isoforms A, B and C are also expressed in placenta, lung, heart, adrenal gland and phaeochromocytoma; isoforms A and C in liver, testis and small intestine; isoform B, C and D in endothelial cells and umbilical vein smooth muscle cells; isoforms C and D in saphenous vein cells, and isoform C in kidney.

亚细胞定位

Cell membrane