E2F相关磷蛋白 (EAPP)
E2F相关磷蛋白 (EAPP)
Q56P03功能描述
可能在主要E2F1活性的精细调节中发挥重要作用，即细胞周期的调节和细胞凋亡的诱导。促进S期进入，并抑制p14(ARP)表达。 {ECO:0000269|PubMed:15716352}。
组织特异性
Ubiquitously expressed. Highest levels in heart, placenta, skeletal muscle and pancreas. Lower levels in brain, lung and kidney. In the brain, expressed in all regions with high levels in the cerebellum and cerebral cortex. Expressed in COS1 and transformed skin fibroblasts.
亚细胞定位
Cytoplasm. Nucleus.
关键词