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DNER Q8NFT8

Delta和Notch样表皮生长因子相关受体

蛋白质信息 (UniProt)

Delta和Notch样表皮生长因子相关受体

Q8NFT8

功能描述

NOTCH1通路的激活剂。可能在星形胶质细胞生成过程中介导神经元-胶质细胞相互作用(通过相似性)。{ECO:0000250}。

组织特异性

Expressed in brain, spinal cord and adrenal gland.

亚细胞定位

Cell membrane; Single-pass type I membrane protein. Note=Present on the membrane of dendrites and cell bodies but excluded from axonal membrane. Also found in early endosomes in the somatodendritic region (By similarity).

关键词

Activator Calcium Cell membrane Disulfide bond EGF-like domain Glycoprotein Membrane Notch signaling pathway Phosphoprotein Proteomics identification