DNASE2B Q8WZ79

脱氧核糖核酸酶-2-β (EC 3.1.22.1) (DNase II样酸性DNase) (DNase2样酸性DNase) (脱氧核糖核酸酶II beta) (DNase II beta) (核酸内切酶DLAD)

蛋白质信息 (UniProt)

脱氧核糖核酸酶-2-β (EC 3.1.22.1) (DNase II样酸性DNase) (DNase2样酸性DNase) (脱氧核糖核酸酶II beta) (DNase II beta) (核酸内切酶DLAD)

Q8WZ79

功能描述

在酸性条件下水解DNA。活性不需要二价阳离子。参与晶状体细胞分化过程中核DNA的降解。 {ECO:0000269|PubMed:11700027, ECO:0000269|PubMed:12944971}。

组织特异性

Highly expressed in the eye lens and in salivary gland. Detected at lower levels in lung, prostate and lymph node. Isoform 2 is lung specific.

亚细胞定位

Lysosome

关键词

Alternative splicing Endonuclease Glycoprotein Hydrolase Lysosome Nuclease Proteomics identification Reference proteome Signal

UniProt: Q8WZ79

NCBI Gene

GeneCards