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DEFB109B Q30KR1

β-防御蛋白 109B (DEFB-109) (HBD9) (防御蛋白 β 109B)

蛋白质信息 (UniProt)

β-防御蛋白 109B (DEFB-109) (HBD9) (防御蛋白 β 109B)

Q30KR1

功能描述

具有抗菌活性。 {ECO:0000250}。

组织特异性

Constitutively expressed in all regions of the ocular surface with predominant expression in the uppermost layers of the corneal epithelium and lower levels in basal layers (at protein level) (PubMed:20375350). Also detected in some keratocytes in the corneal stroma (at protein level) (PubMed:20375350). Expressed in all layers of the limbal epithelium with no expression found in limbal keratocytes (at protein level) (PubMed:20375350). Strongly expressed in the conjunctival epithelium with decreased expression in basal layers (at protein level) (PubMed:20375350). Also strongly expressed in tonsil tissue (at protein level) (PubMed:20375350).

亚细胞定位

Secreted

关键词

Antibiotic Antimicrobial Defensin Disulfide bond Reference proteome Secreted Signal