β-防御素 103 (β-防御素 3) (BD-3) (DEFB-3) (HBD3) (hBD-3) (防御素，β 103) (防御素样蛋白)
β-防御素 103 (β-防御素 3) (BD-3) (DEFB-3) (HBD3) (hBD-3) (防御素，β 103) (防御素样蛋白)
P81534功能描述
对革兰氏阳性菌金黄色葡萄球菌(S.aureus)和化脓性链球菌(S.pyogenes)、革兰氏阴性菌铜绿假单胞菌(P.aeruginosa)和大肠杆菌(E.coli)以及酵母菌白色念珠菌(C.albicans)表现出抗菌活性。能杀灭多重耐药金黄色葡萄球菌和耐万古霉素屎肠球菌(E.faecium)。未观察到显著的溶血活性。 {ECO:0000269|PubMed:11085990}。
组织特异性
Highly expressed in skin and tonsils, and to a lesser extent in trachea, uterus, kidney, thymus, adenoid, pharynx and tongue. Low expression in salivary gland, bone marrow, colon, stomach, polyp and larynx. No expression in small intestine.
亚细胞定位
Secreted.
关键词