含双皮质素结构域蛋白2 (Protein RU2S)
含双皮质素结构域蛋白2 (Protein RU2S)
Q9UHG0功能描述
在抑制经典Wnt信号通路中发挥作用的蛋白质 (PubMed:25557784)。可能参与大脑新皮层发育过程中的神经元迁移 (By similarity)。参与纤毛发生和纤毛长度的控制 (PubMed:25601850, PubMed:27319779)。 {ECO:0000250|UniProtKB:D3ZR10, ECO:0000269|PubMed:25557784, ECO:0000269|PubMed:25601850, ECO:0000269|PubMed:27319779}。
组织特异性
Ubiquitously expressed. In brain, highly expressed in the entorhinal cortex, inferior temporal cortex, medial temporal cortex, hypothalamus, amygdala and hippocampus (PubMed:10601354, PubMed:16278297). Expressed in liver by cholangiocytes, the epithelial cells of the bile ducts (at protein level) (PubMed:27319779).
亚细胞定位
Cell projection, cilium
关键词