天冬氨酸--tRNA连接酶，细胞质 (EC 6.1.1.12) (天冬氨酰-tRNA合成酶) (AspRS) (细胞增殖诱导基因40蛋白)
天冬氨酸--tRNA连接酶，细胞质 (EC 6.1.1.12) (天冬氨酰-tRNA合成酶) (AspRS) (细胞增殖诱导基因40蛋白)
P14868功能描述
以两步反应催化氨基酸特异性连接到其同源tRNA：氨基酸(AA)首先被ATP激活形成AA-AMP，然后转移到tRNA的受体末端。 {ECO:0000250|UniProtKB:P15178}。
组织特异性
Expression in the developing and adult brain shows similar patterns. Highly expressed in the ventricular and subventricular zones, including hippocampal subfields, the midlateral temporal cortex and the frontal polar cortex. The cerebellum, cerebral cortex, hippocampus, and lateral ventricle show preferential neuronal expression. Expression in the peripheral neurons is evident in the colon.
亚细胞定位
Cytoplasm, cytosol
关键词