DAOA P59103

D-氨基酸氧化酶调节因子 (Protein G72)

功能描述

可能抑制DAO (D-amino acid oxidase) 和SOD1活性并促进其降解 (PubMed:18544534, PubMed:20521334, PubMed:21679769, PubMed:30037290)。相反地，也有研究提出其作为DAO激活因子的功能 (PubMed:12364586, PubMed:24362575, PubMed:29114206)。可能刺激DDO (D-aspartate oxidase) 的降解 (PubMed:37805834)。可能在线粒体分裂中发挥作用 (PubMed:17684499)。 {ECO:0000269|PubMed:12364586, ECO:0000269|PubMed:17684499, ECO:0000269|PubMed:18544534, ECO:0000269|PubMed:20521334, ECO:0000269|PubMed:21679769, ECO:0000269|PubMed:24362575, ECO:0000269|PubMed:29114206, ECO:0000269|PubMed:30037290, ECO:0000269|PubMed:37805834}。

组织特异性

Expressed in the amygdala and in astrocytes of the cortex (at protein level) (PubMed:12364586, PubMed:17684499, PubMed:18544534). Expressed in the caudate nucleus, spinal cord and testis (PubMed:12364586).

亚细胞定位

Cytoplasm, cytosol