CYFIP2 Q96F07

胞质FMR1相互作用蛋白2 (p53诱导蛋白121)

蛋白质信息 (UniProt)

胞质FMR1相互作用蛋白2 (p53诱导蛋白121)

Q96F07

功能描述

参与T细胞粘附和p53/TP53依赖性细胞凋亡诱导。不结合RNA。作为WAVE1复合物的组分，为BDNF-NTRK2内体运输和来自早期内体的信号传导所必需(By similarity)。 {ECO:0000250|UniProtKB:Q5SQX6, ECO:0000269|PubMed:10449408, ECO:0000269|PubMed:15048733, ECO:0000269|PubMed:17245118}.

组织特异性

Expressed in T-cells. Increased expression is observed in CD4(+) T-lymphocytes from patients with multiple sclerosis (at protein level).

亚细胞定位

Cytoplasm

关键词

Acetylation Alternative splicing Apoptosis Cell adhesion Cytoplasm Disease variant Epilepsy Nucleus Proteomics identification Reference proteome

外部链接

UniProt: Q96F07

NCBI Gene

GeneCards