CXCL14 O95715

C-X-C基序趋化因子14 (趋化因子BRAK) (MIP-2G) (小诱导细胞因子B14)

功能描述

对中性粒细胞的强效趋化因子，对树突状细胞作用较弱。对T细胞、B细胞、单核细胞、自然杀伤细胞或粒细胞无趋化作用。在集落形成实验中不抑制髓系祖细胞的增殖。 {ECO:0000269|PubMed:10049774, ECO:0000269|PubMed:10946286}。

组织特异性

Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Highly expressed in normal tissue without inflammatory stimuli and infrequently expressed in cancer cell lines. Weakly expressed in monocyte-derived dendritic cells. Not detected in lung or unstimulated peripheral blood lymphocytes.

亚细胞定位

Secreted.