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CPNE3 O75131

钙连蛋白-3 (钙连蛋白 III)

蛋白质信息 (UniProt)

钙连蛋白-3 (钙连蛋白 III)

O75131

功能描述

钙依赖性磷脂结合蛋白,在响应生长因子heregulin刺激的ERBB2介导的肿瘤细胞迁移中发挥作用 (PubMed:20010870)。 {ECO:0000269|PubMed:20010870}。

组织特异性

Expressed in breast and weakly in prostate and ovarian tissues (PubMed:20010870). Expressed in neutrophils (at protein level) (PubMed:12949241). Widely expressed (PubMed:11041869). Expressed in the brain. Expressed in neutrophil precursors from the bone marrow and peripheral blood (PubMed:12949241). Expressed in primary breast tumors and ovarian endometrioid adenocarcinoma (PubMed:20010870).

亚细胞定位

Nucleus

关键词

Calcium Cell junction Cell membrane Cytoplasm Direct protein sequencing Membrane Metal-binding Nucleus Phosphoprotein Proteomics identification