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COL15A1 P39059

XV型胶原α-1链 [裂解为:Restin (Endostatin-XV) (Related to endostatin) (Restin-I); Restin-2 (Restin-II); Restin-3 (Restin-III); Restin-4 (Restin-IV)]

蛋白质信息 (UniProt)

XV型胶原α-1链 [裂解为:Restin (Endostatin-XV) (Related to endostatin) (Restin-I); Restin-2 (Restin-II); Restin-3 (Restin-III); Restin-4 (Restin-IV)]

P39059

功能描述

结构蛋白,稳定心脏和骨骼肌中的微血管和肌肉细胞。 {ECO:0000269|PubMed:10049780}.; FUNCTION: Restin有效抑制血管生成。 {ECO:0000250}.

组织特异性

Detected in fibroblasts and urine (at protein level) (PubMed:25326458, PubMed:36213313, PubMed:37453717). Detected in placenta (at protein level) (PubMed:32337544). Expressed predominantly in internal organs such as adrenal gland, pancreas and kidney.

亚细胞定位

Secreted, extracellular space, extracellular matrix

关键词

3D-structure Angiogenesis Cell adhesion Collagen Developmental protein Differentiation Direct protein sequencing Disulfide bond Extracellular matrix Glycoprotein