CNNM2 Q9H8M5

金属转运蛋白 CNNM2 (古保守结构域包含蛋白 2) (Cyclin-M2)

功能描述

二价金属阳离子转运蛋白。以 Mg(2+) > Co(2+) > Mn(2+) > Sr(2+) > Ba(2+) > Cu(2+) > Fe(2+) 的顺序介导二价金属阳离子的转运 (By similarity)。 {ECO:0000250|UniProtKB:Q3TWN3}。

组织特异性

Widely expressed. Expressed at higher level in brain, kidney and placenta, while it is weakly expressed in skeletal muscle. In the kidney, it is expressed in the distal convoluted tubule and the thick ascending limb of Henle loop.

亚细胞定位

Cell membrane