C-Maf诱导蛋白 (c-Mip) (截短型C-Maf诱导蛋白) (Tc-Mip)
C-Maf诱导蛋白 (c-Mip) (截短型C-Maf诱导蛋白) (Tc-Mip)
Q8IY22功能描述
在T细胞信号通路中发挥作用。Isoform 2可能在T辅助细胞2 (Th2) 信号通路中发挥作用，并且似乎代表了第一个将T细胞受体介导的信号与c-Maf Th2特异性因子的激活联系起来的近端信号蛋白。 {ECO:0000269|PubMed:12939343, ECO:0000269|PubMed:15128042}。
组织特异性
Isoform 1 is expressed in peripheral blood mononuclear cells and kidney. Lower expression in brain and liver. Expression is down-regulated in activated cells. Isoform 2 is expressed in lymphocyte precursors, however, expression shuts down during maturation and differentiation in thymus and fetal liver.
亚细胞定位
Nucleus
关键词