返回首页

CMAS Q8NFW8

N-酰基神经氨酸胞苷酰转移酶 (EC 2.7.7.43) (CMP-N-乙酰神经氨酸合酶) (CMP-NeuNAc合酶)

蛋白质信息 (UniProt)

N-酰基神经氨酸胞苷酰转移酶 (EC 2.7.7.43) (CMP-N-乙酰神经氨酸合酶) (CMP-NeuNAc合酶)

Q8NFW8

功能描述

催化N-乙酰神经氨酸(NeuNAc)活化生成胞苷5'-单磷酸N-乙酰神经氨酸(CMP-NeuNAc),这是添加唾液酸所需的底物。对NeuNAc、N-羟乙酰神经氨酸(Neu5Gc)或2-酮-3-脱氧-D-甘油-D-半乳糖-壬酸(KDN)具有一定的活性。

组织特异性

Ubiquitously expressed. Expressed in pancreas, kidney, liver, skeletal muscle, lung, placenta, brain, heart, colon, PBL, small intestine, ovary, testis, prostate, thymus and spleen.

亚细胞定位

Nucleus

关键词

Acetylation Alternative splicing Direct protein sequencing Methylation Nucleotidyltransferase Nucleus Proteomics identification Reference proteome Transferase