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CLINT1 Q14677

网格蛋白相互作用蛋白1 (位于反式高尔基体区域的网格蛋白相互作用蛋白) (Clint) (Enthoprotin) (Epsin-4) (Epsin相关蛋白) (EpsinR)

蛋白质信息 (UniProt)

网格蛋白相互作用蛋白1 (位于反式高尔基体区域的网格蛋白相互作用蛋白) (Clint) (Enthoprotin) (Epsin-4) (Epsin相关蛋白) (EpsinR)

Q14677

功能描述

结合富含磷脂酰肌醇4,5-二磷酸 (PtdIns(4,5)P2) 的膜。可能在通过网格蛋白包被囊泡从反面高尔基网运输到内体过程中发挥作用。刺激网格蛋白组装。 {ECO:0000269|PubMed:12429846, ECO:0000269|PubMed:12538641}。

组织特异性

Ubiquitously expressed at low to intermediate levels.

亚细胞定位

Cytoplasm. Cytoplasm, perinuclear region. Membrane; Peripheral membrane protein. Cytoplasmic vesicle, clathrin-coated vesicle. Note=Found throughout the cell, with the exception of the cell surface. Concentrated in the perinuclear region and associated with clathrin-coated vesicles close to the trans-Golgi network.

关键词

3D-structure Alternative splicing Cytoplasm Cytoplasmic vesicle Direct protein sequencing Endocytosis Lipid-binding Membrane Phosphoprotein Proteomics identification