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CLDND1 Q9NY35

含Claudin结构域蛋白1 (Claudin-25) (膜蛋白 GENX-3745)

蛋白质信息 (UniProt)

含Claudin结构域蛋白1 (Claudin-25) (膜蛋白 GENX-3745)

Q9NY35

功能描述

在负向调节细胞对小分子的通透性方面发挥作用。 {ECO:0000269|PubMed:28244141}。

组织特异性

Widely distributed in the adult CNS with highest expression in the corpus callosum, caudate nucleus, cerebral cortex, medulla, putamen, spinal cord, substantia nigra and subthalamic nucleus. Weak expression was detected in the adult heart.

亚细胞定位

Cell junction, tight junction

关键词

Alternative splicing Cell junction Cell membrane Glycoprotein Membrane Proteomics identification Reference proteome Tight junction Transmembrane Transmembrane helix