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CKLF Q9UBR5

趋化因子样因子 (C32)

蛋白质信息 (UniProt)

趋化因子样因子 (C32)

Q9UBR5

功能描述

可能在骨骼肌的炎症和再生中起重要作用 (PubMed:11415443)。对胚胎发育至关重要 (By similarity)。 {ECO:0000250|UniProtKB:Q9DAS1, ECO:0000269|PubMed:11415443}.; FUNCTION: [Isoform 1]: 对单核细胞、中性粒细胞和淋巴细胞具有趋化反应 (PubMed:11415443)。结合CCR4 (PubMed:16137713)。 {ECO:0000269|PubMed:11415443, ECO:0000269|PubMed:16137713}.

组织特异性

Isoform 1, isoform 2, isoform 3 and isoform 4 have highest expression levels in adult spleen, lung, testis, ovary, peripheral blood leukocyte, placenta, pancreas, and in fetal brain, skeletal muscle, thymus and heart. Lower expression levels in adult skeletal muscle, liver, thymus colon, prostate and fetal spleen and liver.

亚细胞定位

[Isoform 1]: Secreted

关键词

Alternative splicing Chemotaxis Cytokine Membrane Proteomics identification Reference proteome Secreted Transmembrane Transmembrane helix