CFP P27918

备解素 (补体因子P)

蛋白质信息 (UniProt)

备解素 (补体因子P)

P27918

功能描述

补体旁路途径(AP)的正调节因子 (PubMed:16301317, PubMed:20382442, PubMed:28264884, PubMed:9748277)。结合并稳定C3和C5转化酶复合物 (PubMed:16301317, PubMed:20382442, PubMed:28264884, PubMed:9748277)。抑制CFI-CFH介导的Complement C3 beta chain (C3b)降解 (PubMed:31507604)。 {ECO:0000269|PubMed:16301317, ECO:0000269|PubMed:20382442, ECO:0000269|PubMed:28264884, ECO:0000269|PubMed:31507604, ECO:0000269|PubMed:9748277}。

亚细胞定位

Secreted

关键词

3D-structure Complement alternate pathway Disease variant Disulfide bond Glycoprotein Immunity Innate immunity Proteomics identification Reference proteome Repeat

外部链接

UniProt: P27918

NCBI Gene

GeneCards