CFAP251 Q8TBY9

纤毛和鞭毛相关蛋白251 (含WD重复蛋白66)

功能描述

参与精子运动 (PubMed:30122540, PubMed:30122541)。可能还通过其在轴突辐射辐组装中的作用调节纤毛运动 (By similarity)。 {ECO:0000250|UniProtKB:A8IRK7, ECO:0000250|UniProtKB:Q24DE2, ECO:0000269|PubMed:30122540, ECO:0000269|PubMed:30122541}。

组织特异性

Isoform 1 is highly expressed in testis and, at lower levels, in lung. Very low levels are detected in kidney and brain (PubMed:30122540). In testis, expressed in spermatozoa (at protein level) (PubMed:30122540, PubMed:30122541). Isoform 2 is not detected in testis, lung, kidney, nor in brain (PubMed:30122540).

亚细胞定位

Cytoplasm, cytoskeleton, cilium axoneme