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CEP85L Q5SZL2

85 kDa样中心体蛋白 (血清学定义的乳腺癌抗原 NY-BR-15)

蛋白质信息 (UniProt)

85 kDa样中心体蛋白 (血清学定义的乳腺癌抗原 NY-BR-15)

Q5SZL2

功能描述

在神经细胞迁移中发挥重要作用。 {ECO:0000269|PubMed:32097630}。

组织特异性

Isoform 1 and isoform 4 are expressed in spleen, lymph, thymus, tonsil and peripheral blood leukocytes, with isoform 1 expressed at higher levels. Isoform 4 is detected in K-562 leukemia cells and in the blood of precursor T lymphoblastic lymphoma (T-ALL) patients.

亚细胞定位

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome

关键词

Alternative splicing Chromosomal rearrangement Coiled coil Cytoplasm Cytoskeleton Disease variant Lissencephaly Phosphoprotein Proteomics identification Reference proteome