CDKL5 O76039

细胞周期蛋白依赖性激酶样5 (EC 2.7.11.22) (丝氨酸/苏氨酸-蛋白激酶9)

蛋白质信息 (UniProt)

细胞周期蛋白依赖性激酶样5 (EC 2.7.11.22) (丝氨酸/苏氨酸-蛋白激酶9)

O76039

功能描述

介导MECP2的磷酸化 (PubMed:15917271, PubMed:16935860)。可能调节纤毛发生 (PubMed:29420175)。 {ECO:0000269|PubMed:15917271, ECO:0000269|PubMed:16935860, ECO:0000269|PubMed:29420175}。

组织特异性

Expressed in brain, lung, kidney, prostate, ovary, placenta, pancreas and testis.; TISSUE SPECIFICITY: [Isoform 2]: Predominant transcript in brain.

亚细胞定位

Nucleus

关键词

3D-structure Alternative splicing ATP-binding Cell projection Chromosomal rearrangement Cytoplasm Cytoskeleton Disease variant Epilepsy Intellectual disability

外部链接

UniProt: O76039

NCBI Gene

GeneCards