CBLL2 Q8N7E2

E3泛素蛋白连接酶CBLL2 (EC 2.3.2.27) (Cbl原癌基因样蛋白2) (RING型E3泛素转移酶ZNF645) (锌指蛋白645) (c-Cbl样蛋白2)

蛋白质信息 (UniProt)

E3泛素蛋白连接酶CBLL2 (EC 2.3.2.27) (Cbl原癌基因样蛋白2) (RING型E3泛素转移酶ZNF645) (锌指蛋白645) (c-Cbl样蛋白2)

Q8N7E2

功能描述

E3泛素连接酶，催化泛素部分共价附着到底物蛋白上 (PubMed:20657603)。可能作用于酪氨酸磷酸化的SRC底物 (PubMed:22252131)。 {ECO:0000269|PubMed:20657603, ECO:0000269|PubMed:22252131}。

组织特异性

Exclusively expressed in testis and sperm, including spermatocytes, round and elongated spermatids, and Leydig cells.

亚细胞定位

Cytoplasm

关键词

Cytoplasm Metal-binding Proteomics identification Reference proteome Transferase Ubl conjugation pathway Zinc Zinc-finger

UniProt: Q8N7E2

NCBI Gene

GeneCards