CARTPT Q16568

可卡因-苯丙胺调节转录蛋白 [裂解为：CART(1-39)；CART(42-89)]

功能描述

功能：饱腹因子，与leptin和neuropeptide Y的作用密切相关；这种厌食肽抑制正常和饥饿诱导的进食，并完全阻断由neuropeptide Y诱导且受下丘脑leptin调节的进食反应。它在体外促进神经元发育和存活。 {ECO:0000269|PubMed:9590691}。

组织特异性

Hypothalamus. Found in neurons of the ventrolateral part of the arcuate nucleus, in the external zone of the median eminence, and also found in terminals in the periventricular part of the paraventricular nucleus.

亚细胞定位

Secreted