CABYR O75952

钙结合酪氨酸磷酸化调节蛋白 (钙结合蛋白 86) (癌/睾丸抗原 88) (CT88) (纤维鞘蛋白 II) (纤维鞘蛋白-2) (FSP-2) (睾丸特异性钙结合蛋白 CBP86)

功能描述

可能作为运动功能和头部相关功能（如获能和顶体反应）的调节因子发挥作用。Isoform 1 在体外结合钙。Isoform 2 和 isoform 6 可能结合钙。Isoform 3 和 isoform 5 在体外不结合钙。Isoform 4 可能不结合钙。

组织特异性

Expressed in elongating spermatids and spermatozoa (at protein level). Isoform 1 is expressed in testis. Isoform 3 and isoform 5 are also expressed in brain, pancreas and numerous brain tumors.

亚细胞定位

Cytoplasm, cytoskeleton. Cell projection, cilium, flagellum. Note=Localized to fibrous sheath including the surface of the longitudinal columns and ribs of the principal piece of sperm flagella.; SUBCELLULAR LOCATION: [Isoform 1]: Nucleus. Cytoplasm. Cell projection, cilium, flagellum. Note=According to PubMed:15752768, isoform 1, isoform 3 and isoform 5 are both nuclear and cytoplasmic.; SUBCELLULAR LOCATION: [Isoform 3]: Nucleus. Cytoplasm. Cell projection, cilium, flagellum. Note=According to PubMed:15752768, isoform 1, isoform 3 and isoform 5 are both nuclear and cytoplasmic.; SUBCELLULAR LOCATION: [Isoform 5]: Nucleus. Cytoplasm. Cell projection, cilium, flagellum. Note=According to PubMed:15752768, isoform 1, isoform 3 and isoform 5 are both nuclear and cytoplasmic.