CA9 Q16790

碳酸酐酶 9 (EC 4.2.1.1) (碳酸脱水酶 IX) (碳酸酐酶 IX) (CA-IX) (CAIX) (膜抗原 MN) (P54/58N) (肾细胞癌相关抗原 G250) (RCC相关抗原 G250) (pMW1)

蛋白质信息 (UniProt)

碳酸酐酶 9 (EC 4.2.1.1) (碳酸脱水酶 IX) (碳酸酐酶 IX) (CA-IX) (CAIX) (膜抗原 MN) (P54/58N) (肾细胞癌相关抗原 G250) (RCC相关抗原 G250) (pMW1)

Q16790

功能描述

催化二氧化碳和水与碳酸解离离子（即碳酸氢根和氢离子）之间的相互转化。 {ECO:0000269|PubMed:17314045, ECO:0000269|PubMed:17705204, ECO:0000269|PubMed:18703501, ECO:0000269|PubMed:19186056, ECO:0000269|PubMed:19206230, ECO:0000269|PubMed:19805286}.

组织特异性

Expressed primarily in carcinoma cells lines. Expression is restricted to very few normal tissues and the most abundant expression is found in the epithelial cells of gastric mucosa.

亚细胞定位

Nucleus

关键词

3D-structure Cell membrane Cell projection Direct protein sequencing Disulfide bond Glycoprotein Lyase Membrane Metal-binding Nucleus

外部链接

UniProt: Q16790

NCBI Gene

GeneCards