CA12 O43570

碳酸酐酶 12 (EC 4.2.1.1) (碳酸脱水酶 XII) (碳酸酐酶 XII) (CA-XII) (肿瘤抗原 HOM-RCC-3.1.3)

功能描述

二氧化碳的可逆水合。 {ECO:0000269|PubMed:26911677}。

组织特异性

Highly expressed in colon, kidney, prostate, intestine and activated lymphocytes. Expressed at much higher levels in the renal cell cancers than in surrounding normal kidney tissue. Moderately expressed in pancreas, ovary and testis. Expressed in sweat glands and bronchiolar epithelium (PubMed:26911677).

亚细胞定位

Membrane; Single-pass type I membrane protein. Cell membrane