返回首页

C1GALT1C1 Q96EU7

C1GALT1特异性伴侣蛋白1 (C38H2样蛋白1) (C38H2-L1) (核心1 β1,3-半乳糖基转移酶2) (C1Gal-T2) (C1GalT2) (核心1 β3-Gal-T2) (核心1 β3-半乳糖基转移酶特异性分子伴侣)

蛋白质信息 (UniProt)

C1GALT1特异性伴侣蛋白1 (C38H2样蛋白1) (C38H2-L1) (核心1 β1,3-半乳糖基转移酶2) (C1Gal-T2) (C1GalT2) (核心1 β3-Gal-T2) (核心1 β3-半乳糖基转移酶特异性分子伴侣)

Q96EU7

功能描述

生成1个O-聚糖Gal-beta1-3GalNAc-alpha1-Ser/Thr (T抗原)所需的推定伴侣蛋白,该聚糖是糖蛋白中许多延伸O-聚糖的前体。可能作为特异性分子伴侣,辅助核心1 β-3-半乳糖基转移酶 (C1GALT1) 的折叠/稳定性。 {ECO:0000269|PubMed:12464682, ECO:0000269|PubMed:37216524}。

组织特异性

Ubiquitously expressed. Abundantly expressed in salivary gland, stomach, small intestine, kidney, and testis and at intermediate levels in whole brain, cerebellum, spinal cord, thymus, spleen, trachea, lung, pancreas, ovary, and uterus.

亚细胞定位

Membrane

关键词

Chaperone Disease variant Hemolytic uremic syndrome Membrane Proteomics identification Reference proteome Signal-anchor Transmembrane Transmembrane helix