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BEST4 Q8NFU0

Bestrophin-4 (卵黄状黄斑营养不良2样蛋白2)

蛋白质信息 (UniProt)

Bestrophin-4 (卵黄状黄斑营养不良2样蛋白2)

Q8NFU0

功能描述

配体门控阴离子通道,当被钙 (Ca2+) 激活时,允许阴离子跨细胞膜移动 (PubMed:12907679, PubMed:18400985)。介导碳酸氢根和氯离子的移动 (PubMed:12907679, PubMed:18400985)。 {ECO:0000269|PubMed:12907679, ECO:0000269|PubMed:18400985}。

组织特异性

Predominantly found in colon and the weakly in fetal brain, spinal cord, retina, lung, trachea, testis and placenta.

亚细胞定位

Cell membrane; Multi-pass membrane protein.

关键词

Calcium Cell membrane Chloride Chloride channel Ion channel Ion transport Membrane Metal-binding Proteomics identification Reference proteome