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BARX1 Q9HBU1

同源盒蛋白 BarH 样 1

蛋白质信息 (UniProt)

同源盒蛋白 BarH 样 1

Q9HBU1

功能描述

转录因子,参与颅面发育、牙齿发生和胃器官发生。可能在磨牙与切牙的分化中起作用。在抑制内胚层Wnt活性中发挥作用 (By similarity)。结合于NCAM启动子的一个调节模块。 {ECO:0000250, ECO:0000269|PubMed:9804553}。

组织特异性

Widely expressed. Expressed at higher levels in testis and heart. Detected in craniofacial tissue and adult iris, but not in lymphocytes, fibroblasts, choroid retina, retinal pigment epithelium, kidney, or fetal liver.

亚细胞定位

Nucleus

关键词

3D-structure Alternative splicing DNA-binding Homeobox Nucleus Proteomics identification Reference proteome Transcription Transcription regulation